See companion question here.
I realized that after I posted my previous question that asking that question might be a "solution in search of a problem." I'm interested in what people perceive to be their biggest bottlenecks in doing great work in independent research.
For me what leaps to mind is all of the in-between stuff, like proofreading, LateX issues, graphics, plots, etc. Of course, I've also tried to hire help on some of these fronts with very mixed results (generally negative). So I guess I'd say that fundamentally, independent work can really suffer from its independence (not having various supports and connections that would make it better). Building relationships and collaborations that alleviate these problems is part of being an effective independent researcher.