The numbers are definitely high in absolute terms, though I would guess they are low in comparison to what these people could earn in the private sector. The founder-CEO of an investment firm the size of GiveWell would expect to have compensation in the millions.

I think we should be careful not to forget Dan Palotta’s advice. One of the appealing things about earning to give is that nobody will hassle you for making too much money.

Who is to say that Rob Mather doesn't enjoy a shrimp cocktail now and then?

Serving my fellow man has always been a major source of personal meaning for me. I guess that makes me a do-gooder. From late childhood I had already committed myself to giving 10% of my income after taxes, but at a certain point I realized point that actually money is probably one of the greatest things I had to offer was money (and probably the greatest thing I have to offer strangers). I have the luck and privilege of having more money to offer than most, and its decreasing marginal utility means I can help others without making a big sacrifice myself.

I still donate blood, and might donate a kidney someday, but I suspect that when I look back on my life I'll count my cash donations among my proudest accomplishments.

There's not much to disagree with here, but I downvoted this anyway because it feels uncomfortably close to in-group cheerleading.

LeCun is also probably one of the top people to have worsened the AI safety outlook this decade, and from that perspective perhaps his departure is a good thing for the survival of the world, and thus also Meta’s shareholders?

Manifold market on whether or not this act (or similar legislation) passes: https://manifold.markets/patbl/will-the-end-kidney-deaths-act-or-s

In my experience, you get better advice anyway if you frame the question as though you are a professional. So instead of, "here is a picture of my rash, what do you think?", you say, "A patient has provided this picture of a rash, what is your diagnosis?".