Lead poisoning is a major but historically neglected global health issue. It is caused by exposure to lead — a toxic heavy metal that can impair neurological development, especially in children. Symptoms include cognitive deficits, behavioral issues, infertility, kidney damage, and cardiovascular problems. In 2019, lead exposure was estimated to cause 1.5 million deaths and 36 million DALYs globally — a disease burden comparable to malaria or tuberculosis.

Why this matters for effective altruism

Lead poisoning prevention is:

• Highly impactful – It is a leading cause of developmental delay and lower IQ in children, which in turn harms economic growth and human capital.
• Neglected – Until recently, only ~$15M/year in global funding addressed it — less than 1% of what malaria receives, despite similar burden.
• Tractable – Small-scale interventions (e.g., consumer product regulation, public education, spice sampling) have already had measurable success in countries like Bangladesh and Malawi.

Notable efforts

• Lead Exposure Elimination Project (LEEP): An EA-aligned nonprofit incubated by Charity Entrepreneurship. LEEP helps governments enforce or implement lead paint regulation. It’s shown promising results — reducing the lead-paint market share in Malawi from 67% to 24% in just two years .
• LEAF (Lead Exposure Action Fund): A $100M+ pooled fund led by Open Philanthropy with other donors, supporting grants to reduce exposure through paint, spices, and battery recycling .
• Partnership for a Lead-Free Future: A global collaboration among USAID, UNICEF, Open Philanthropy, and others aiming to end lead poisoning in low- and middle-income countries. Announced in 2024 alongside a Washington Post op-ed by Samantha Power and Alexander Berger .

What works

Evidence from multiple countries shows that:

• Paint regulation, even when laws exist, often requires follow-up monitoring and enforcement to be effective.
• Consumer awareness campaigns (e.g., warning posters about adulterated turmeric) can drastically shift markets for low cost.
• National surveys identifying blood lead levels and sources are an important first step to policy change.

Further Reading

• Power, Samantha & Alexander Berger (2024) Millions of kids are poisoned by lead every year. We have a plan to save them, The Washington Post, September 22.
• Berger, Alexander & Emily Oehlsen (2024) Announcing the Lead Exposure Action Fund, Effective Altruism Forum, September 24.
• Jack & LuciaC (2021) Seven things that surprised us in our first year working in policy – Lead Exposure Elimination Project, Effective Altruism Forum, May 14.