Active Site is a nonprofit working at the frontier of AI and biosecurity, conducting high-stakes, real-world research on how advances in AI could shape biological risk. We’re hiring our first Chief of Staff to build the operational backbone of a fast-moving research organization and help turn ambitious plans into clear, effective execution.

Core responsibilities include:

• Strategy and execution: Run planning and coordination across the organization, translate priorities into owners and timelines, and make sure important decisions actually turn into action
• Cross-functional projects: Lead high-priority initiatives that cut across functions, including new study launches, tooling rollouts, process improvements, and program buildouts
• Study operations: Partner with researchers to operationalize in-person uplift studies, including recruitment and screening, participant communications, logistics, and day-of coordination
• People and HR: Build and run essential people infrastructure, including onboarding, offboarding, employment documentation, benefits administration, and hiring coordination
• Finance: Own project-level budgeting and coordinate with external bookkeepers, accountants, and legal partners to keep operations accurate and on track
• Internal systems: Build the workflows, documentation, knowledge management, and internal tooling that allow Active Site to scale, using AI and automation to reduce manual overhead and increase leverage

Key details:

• Type: full-time
• Compensation: $135,000 to $175,000 per year
• Location: Cambridge, Massachusetts
• Work setup: primarily on-site, with five days per week in office during active in-person studies and greater hybrid flexibility outside study periods

Find more details or apply here.