pretty sure you are talking about the interview with Dr. Nick Beckstead. https://80000hours.org/podcast/episodes/nick-beckstead-giving-billions/#transcript
Just search the page (command key + F) for the number "2000" to find that part of the conversation.
I think maybe it's the episode with Stefan Schubert. I don't actually remember the episode well, but apparently it includes discussion of "Should EA get more involved in politics, or steer clear of it? Would it be a bad idea for a talented graduate to get involved in party politics?" And Schubert co-wrote the related post Hard-to-reverse decisions destroy option value.
Also potentially relevant: