My top three charities in this election are all animal charities. With Animal Charity Evaluators at the top. Sure, that's in part because I work there. And likely influenced by this donation election happening over a US holiday and during a season when even more animals are abused and slaughtered than usual. That's mentally quite taxing and this is a way for me to deal with that.
But I do not just vote this way, I donate this way. A significant part of my salary goes back to ACE.
ACE influenced at least $12.3 million in total donations in our last fiscal year. That includes $6.4 million in counterfactual gifts. That's a direct consequence of our efforts and vital to reduce the suffering of billions of individuals. I see this as evidence of ACE's potential; I think we can do much, much more to engage people who dislike animal abuse to help farmed and wild animals effectively. To do that, the organization needs to be able to invest a bit more in growth.
Last year, for every dollar ACE spent on our charity evaluations and recommendations, we generated $6.05 in donations for highly effective animal charities that wouldn’t have been donated to otherwise. (While a strong multiplier is encouraging, what ultimately matters for animals is the total amount of additional funding directed to effective work—$6.4 million in counterfactual donations. A hypothetical organization could have a multiplier of 100x but only influence $10,000; we’d rather have a lower multiplier and move millions more dollars to where they’ll help animals most. So, don't be too (un)impressed by that number.)
Because of ACE, there are animal lovers who now donate to more effective charities, people who now help more animals. Some of them would otherwise not have given to animal welfare at all. That means more piglets, squabs, chicks, calves, and shrimplets have a chance at a decent life.
You can read more about ACE's meta-fundraising impact and how it was calculated here:
Announcing our Latest Influenced-Giving Metrics - Animal Charity Evaluators

I'm one of the minority who will put forward some GHD orgs this week ;). I think that marginal individual dollars often do the most value funding growing orgs that do one important thing well, so picked Fortify Health, FEM and Lafiya. Full disclosure I know and admire some their founders/workers a bit personally which makes a difference to me too.
I'm not yet convinced about cluster headaches as a cause area, mainly because I'm not convinced that the number of sufferers isas high as claimed. In 13 years as a doctor in Uganda and treating a few thousand patients, I've never seen a convincing case of cluster headache here. However their fundraising post was well written and compelling, and I like new cause areas getting attention so I added them to my vote list.
I've also voted for the Humane League due to their excellent track record and experience doing what I still consider to be the most important/effective animal welfare work - getting hens out of cages. I realise given the ranked choice voting system this will mean that my vote will not go to one of my top ranked GHD orgs, but if it counts at all might actually count towards an animal welfare org lol, which I'm all good with :).
Thanks for the shoutout and for the vote! :)
This is indeed quite surprising! The relatively low prevalence and the lack of recognition of the disease / misdiagnosis may explain it to some extent, but zero patients in 13 years is still very surprising.
(Consider that even an average neurologist only ever sees a few dozen CH patients during their entire career. I asked Opus 4.5 and Gemini 3.0 to estimate how many CH patients an average neurologist in the US sees per year, assuming an annual prevalence of 1/2000 adults, and their responses were 1–2/year and 1/year, respectively. They also think that the average neurologist sees 3–5x (5–10x resp.) more CH patients than the average primary care doctor, but the odds of not encountering a single patient in 13 years should still be very, very low. Will look into this!)
Also, there's almost no epidemiological data on the prevalence of CH in African countries, so the prevalence error bars are large. (In our paper, we included a sensitivity analysis of the most uncertain variables to add some nuance.)
Nice response - i wouldn't take my experience too seriously. i only work part time as a doctor (i run an org) and i could well just have encountered missed the one or two patients with cluster headache. if prevalence is one in 2000 and I've only seen a few thousand patients i probably just missed the guy lol.
I probably shouldn't index off my own experience so much either.
interestingly though there are a lot of conditions with wildly different preference around the world and we don't understand why.