I am less convinced than the median around here that donating to AI safety research organizations is the most important thing to do, and I'd like to share some of my unfiltered thoughts and ask for feedback.

• I think that one can't solve a philosophy or math problem by throwing money at it. This works for engineering problems, as the moon landing or nukes - but if someone funded an institute with 1E9 $  and gave it the task to prove P != NP, I doubt it would succeed. In the history of mathematics, the ideas necessary for big advances tended to come serendipitously from random people who for some reasons had unique insights into problems they may have gotten in the course of considering different things, rather than big focused research programs.
• Relatedly, I hear claims to the effect that "only 100 people in the world work on AI safety, and therefore a marginal person is extremely likely to make a difference." I think that number is off. Everyone who does AI research, is somewhat aware of the problem, and interested in publishing academic-style results (rather than being forced to work on concrete business applications) may come up with ideas relevant to AI alignment.
• Finally, I have a bad feeling about funding researchers in the most expensive places in the world and calculating their salaries based on what they could earn at Google, minus a discount. PhD students and Postdocs - from whom much or most of the important progress in academia comes , as opposed to work organizing and systematizing progress - work for a lot less money, mostly for the prestige (and, possibly, concomitant future earning opportunities) associated with making discoveries. I think that a serious "effective" altruist organisation should consider this.