I don't pretend that this is likely to be highest impact in terms of maximizing global utility, but I have a subjective preference to contribute to causes which help mitigate homelessness in San Francisco (alongside my donations to higher impact causes). Does anyone have suggestions for charities that would be worthwhile recipients?
So my immediate question is whether your preference requires helping the homeless with short feedback loops verifying that said action was impactful. If not, you might want to read up on the case for the economic philosophy of Georgism on Astral Codex Ten if you've never heard of it. It wouldn't surprise me if the best EV case to made for the homeless in San Fransisco is to take a longer view and find LVT levers you can pull on, which would suggest donating to policy stuff or even research.
Though given the benefits of such donations probably wont ever reach the currently suffering homeless, this might not be a suggestion you're looking for. Either way, worth reading up on if you're unaware of it. I only recently (within the last year) became aware of Georgism. Am still learning, but looks very promising.