The views expressed here are my own, not those of the people who provided feedback on the draft.
Summary
- According to the GPT Pain-Track from the Welfare Footprint Project (WFP), “Insecticide-treated nets (ITNs) [link] are not only lethal to mosquitoes but also cause significant suffering before death. When mosquitoes come into contact with the insecticide, their nervous systems are disrupted, leading to intense and prolonged effects. These include uncontrolled movements, convulsions, and muscle spasms, which can last for minutes. This is followed by paralysis and eventual shutdown of their body functions. While effective at reducing disease transmission, ITNs inflict severe pain on mosquitoes during the process, making their impact far from instantaneous or painless”.
- I estimate the ITNs distributed by the Against Malaria Foundation (AMF) in the Democratic Republic of the Congo (DRC) cause 763 times as much harm to mosquitoes as they benefit humans.
- I neglected the effects of ITNs on the number of wild animals because it is super unclear whether they have positive or negative lives. Yet, there is still lots of uncertainty even just in the effects I considered. Just accounting for uncertainty in mosquitoes’ capacity for welfare, I estimate the 5th and 95th percentile harm to mosquitoes caused by ITNs are 0 and 11.5 k times their benefits to humans. So it is unclear to me whether ITNs increase or decrease welfare.
- I believe the large uncertainty about the effects of human welfare interventions on wild (and farmed) animals should push one towards prioritising:
- I estimate people donating to AMF can offset the harm ITNs cause to mosquitoes pretty cheaply, donating 1.19 % as much to SWP as to AMF. This fraction is more robust than it may seem because the harm ITNs cause to mosquitoes is decently proportional to the cost-effectiveness of SWP.
- I would move any marginal donations from helping humans to helping invertebrates, so I would not donate to AMF. Nonetheless, I think directing a small fraction (10 %?) of one’s donations to helping invertebrates would be a good compromise to offset potential negative effects. I encourage people donating to animal welfare to do this too.
Context
I strongly endorse expectational total hedonistic utilitarianism (increasing happiness, and decreasing suffering), and think one can reasonably make comparisons across species based on Rethink Priorities’ (RP’s) median welfare ranges. This post explores potential implications of having these 2 views. I think the takeaways are basically the same under desire theories, as beings want to be happy, and not suffer. However, they may differ significantly if you strongly reject impartiality, or consider RP’s median welfare ranges dramatically overestimate animals’ capacity for welfare.
Harm caused to mosquitoes
Here are my calculations. I describe them below.
According to Open Philanthropy (OP), “GiveWell uses moral weights for child deaths that would be consistent with assuming 51 years of foregone life in the DALY framework [this one] (though that is not how they reach the conclusion)”. I guess 1 mosquito-year of fully healthy life is 1.3 % as good as 1 human-year of fully healthy life, which is RP’s median welfare range of black soldier flies. So I think 3.92 k mosquito-years of fully healthy life are as good as the additional human welfare from saving 1 life under GW’s moral weights.
I guess disabling pain is 10 times as intense as fully healthy life, in which case 2.4 hours (= 24/10) of disabling pain neutralise 1 day of fully healthy life. Consequently, I infer that 392 mosquito-years of disabling pain neutralise the additional human welfare from saving 1 life under GW’s moral weights.
GW’s last grant to AMF, as available on their database on 15 January 2025, was of 41 M$, and targeted DRC, for which GW calculates a cost per distributed net and life saved of 6.78 $ and 5.10 k$. These imply AMF has to distribute 752 nets to save a life in DRC. As a result, 0.522 mosquito-years of disabling pain neutralise the benefits to humans of distributing a net in DRC.
GW calculates that nets in DRC effectively last 1.2 years. As a consequence, 0.435 mosquito-years of disabling pain neutralise the benefits to humans of 1 net-year in DRC.
I guess nets kill 1 mosquito every hour, or 0.0167 mosquitos per net-minute. Accordingly, 26.1 mosquito-minutes of disabling pain per mosquito killed by nets neutralise the benefits to humans of GW’s last grant to AMF.
I estimate mosquitoes’ welfare loss per mosquito killed by nets is equivalent to 19.9 k mosquito-minutes of disabling pain. I got this based on:
3 sets of estimates for the time in the 4 categories of pain defined by WFP for the 4 stages described by their GPT Pain-Track for the impact of ITNs on mosquitoes:
Initial contact. “This stage starts as soon as the mosquito touches the net. The chemicals on the net begin to pass through the mosquito’s outer layer and interfere with its nerves. This leads to quick twitching or slight movements as the nerves start to malfunction”.
Toxic excitation. “In this phase, the mosquito starts moving uncontrollably. It may flap its wings excessively or shake as the chemicals overwhelm its nervous system. This stage is intense and chaotic, as the mosquito's body reacts to the disruption”.
Paralysis onset. “The mosquito’s movements slow down as its muscles stop working properly. It becomes unable to fly or move, eventually becoming still. This phase is marked by a gradual loss of control over its body”.
Pre-mortem decline. “In this final stage, the mosquito becomes completely still as its body shuts down. Its muscles and nerves stop working entirely, and it is on the brink of death. The length of this phase depends on how much chemical it absorbed”.
Aggregating the 3 sets of estimates with the geometric mean, as I guess each component estimate of the time in pain follows a lognormal distribution.
- My guesses that:
- Annoying pain is 1 % (= 0.1/10) as intense as disabling pain.
- Hurtful pain is 10 % (= 1/10) as intense as disabling pain.
- Excruciating pain is 10 k (= 100*10^3/10) times as intense as disabling pain. This leads to roughly 100 % of the welfare loss being caused by excruciating pain. So, if one thinks excruciating pain is, for example, 10 % as intense as I supposed, the welfare loss will be 10 % as large.
I conclude GW’s last grant to AMF of 41 M$ caused 763 times as much harm to mosquitoes via ITNs as it benefited humans. Here are a few ways of the harm caused to mosquitoes via ITNs to be as large as the benefits to humans:
- Excruciating pain 0.131 % (= 1/763) as intense (assuming this only negligibly increases the benefits to humans).
- If so, I would guess excruciating pain to be 131 (= 0.00131*100*10^3) times as intense as a practically maximally happy life.
- As a result, 11.0 min (= 24*60/131) of excruciating pain would neutralise 1 day of a practically maximally happy life. In other words, it would be hedonically neutral to have a practically maximally happy life plus 11.0 min every day of “scalding and severe burning events [in large parts of the body]”, or “dismemberment, or extreme torture”. I would consider this life hedonically very bad.
- Mosquitoes’ capacity for welfare 0.131 % as high (relative to humans).
- RP’s median welfare range of black soldier flies is 3.92 % (= 0.013/0.332) their median welfare range of chickens. So the above update corresponds to 2.05 (= ln(0.00131)/ln(0.0392)) updates relatively as large as going from chickens to black soldier flies.
- Excruciating pain 3.62 % (= 0.00131^(1/2)) as intense, and mosquitoes’ capacity for welfare 3.62 % as high.
- If so, I would guess excruciating pain to be 3.62 k (= 0.0362*100*10^3) times as intense as a practically maximally happy life, and estimate 1 day of this would be neutralised with 23.9 s (= 24*60^2/(3.62*10^3)) of excruciating pain.
- The update on the capacity for welfare corresponds to 1.02 (= ln(0.0362)/ln(0.0392)) updates relatively as large as going from chickens to black soldier flies.
Discussion
It would be great if there were ITNs which painlessly kill mosquitoes, but it looks like there are not any. According to Claude:
- Insecticide-treated nets (ITNs) work through chemicals that affect mosquitoes’ nervous systems, leading to either:
- Rapid knockdown and death
- Repellent effects that deter contact
- All current effective ITN insecticides (pyrethroids, chlorfenapyr, etc.) work by disrupting neural function, which would cause distress to the mosquito's nervous system before death.
- Non-toxic alternatives like physical barriers or natural repellents either:
- Don’t achieve the same efficacy in preventing malaria
- Still cause distress through sensory irritation
I neglected the effects of ITNs on the number of wild animals because it is super unclear whether they have positive or negative lives. Yet, there is still lots of uncertainty even just in the effects I considered. RP’s 5th and 95th percentile welfare ranges of black soldier flies are 0 and 15.1 (= 0.196/0.013) times their median. This suggests that, even ignoring effects on the number of wild animals, and just accounting for uncertainty in mosquitoes’ capacity for welfare, the 5th and 95th percentile harm to mosquitoes caused by ITNs are 0 and 11.5 k (= 15.1*763) times their benefits to humans. So it is unclear to me whether ITNs increase or decrease welfare.
I believe the large uncertainty about the effects of human welfare interventions on wild (and farmed) animals should push one towards prioritising:
- Animal welfare interventions improving the conditions of animals instead of decreasing the number of animals with negative lives, or increasing the number of animals with positive lives. I recommend donating to the Shrimp Welfare Project (SWP), which I estimate has been 64.3 k times as cost-effective as GW’s top charities (neglecting their effects on animals).
- Learning more about helping invertebrates, whose total capacity for welfare vastly exceeds that of vertebrates. I recommend donating to (I ordered the organisations alphabetically):
- The Arthropoda Foundation. Their research priorities are humane slaughter protocols, stocking densities and substrate research, and automated welfare assessment.
- The Wild Animal Initiative (WAI). For instance:
- They intend “to use current and new funding” for, among other activities, “Conducting an analysis of agricultural pest control to better understand the best targets for welfare interventions — first identifying scientific gaps and then developing research plans to help fill them”.
- I estimate paying farmers to use more humane pesticides to decrease the suffering of wild insects is 23.7 k times as cost-effective as GW’s top charities.
No one from the animal welfare organisations I mentioned above reviewed the draft of this post. As always unless stated otherwise, I am speaking for myself.
I strongly endorse maximising expected welfare. Nevertheless, I think donating to the above organisations is even better if one intrinsically cares about minimising the probability of causing harm.
I estimate people donating to AMF can offset the harm ITNs cause to mosquitoes pretty cheaply, donating 1.19 % (= 763/(64.3*10^3)) as much to SWP as to AMF. This fraction is more robust than it may seem because the harm ITNs cause to mosquitoes is decently proportional to the cost-effectiveness of SWP. Under my views:
I would move any marginal donations from helping humans to helping invertebrates, so I would not donate to AMF. Nonetheless, I think directing a small fraction (10 %?) of one’s donations to helping invertebrates would be a good compromise to offset potential negative effects. I encourage people donating to animal welfare to do this too. Decreasing the consumption of animal-based foods, especially beef, has major effects on wild animals, and improving animals’ conditions can indirectly change their consumption too, although arguably much less. On the impact of human diet on animal welfare, Michael St. Jules suggested Matheny (2005), this and these posts from Brian Tomasik, this post from Carl Shulman, and Fischer (2018). There is also the sequence Human impacts on animals created by Michael.
Acknowledgements
Thanks to CB for the comment which motivated me to make this post. Thanks to Abraham Rowe, CB, and Michael St. Jules for feedback on the draft.
I think this is an interesting post and warrants discussion, but I ended up strongly downvoting because I don't want this to be the kind of discussion which is front and center on our public EA forum for external facing reasons and PR risk. This might well be the wrong response and many people might disagree with me on this which is fair enough.
I'll also flag that find the idea that saving poor kids' lives might be bad on the account of mosquito suffering makes me emotionally and almost physically squeamish, even if intellectually I think its an important discussion to have.
After flagging my biases, it still seems to me Vasco's analysis swings unnecessarily mosquito friendly, to the point where it almost feels motivated. I'm not saying it is motivated but there is a lack of "conservatism" or sanity checks in this estimate.
There's no thought of counterfactuals. Someone mentioned hat mosquitos will die anyway, and that could be painful too which is true. More to the point, without the nets to protect us other mosquito slaughtering options would be used and actually have been used as a kind of net alternative include...
- Indoor residual spraying, which slaughters mosquitos on mass with similar chemicals
- Mass poisoning of water bodies through chemicals (in the past DDT which surely caused animals higher in the food chain to suffer)
If AMF and the nets weren't doing their job, I would guess the alternatives might be at least as bad for mosquito welfare.
"I don't know where exactly to draw the line here, but 14.3 mosquito days of excruciating suffering for one happy human life seems clearly beyond it."
I ended up strong downvoting your comment because I don't want concerns about PR risk to be top comment on this post.
I trust EA as a high quality source of information on charity, mainly because EA presents itself as impartial to causes, objective, and acts with honesty and integrity. This post seemed well researched and made in good faith to me, and your willingness to censor it for making the movement look bad makes me trust the quality of information on this forum seriously.
If you believe something is false, just criticize it for being false.
If you don't like it, just say you don't like it.
Your personal favor towards malaria nets, and your personal distaste for this post is totally okay. I just don't think PR considerations should be primarily what EA forum is about.
It is also counterproductive. To put it rudely, you are not cool enough to care about PR. You are not ready to critique aesthetics, vibes, and taste-making; not without making things worse. The forum is not a good canvas. It is not designed to be. It should not try to be.
Please continue to do lots of research, math, and compassion. If you must care about appearance, please go about it in a positive, truth-seeking way - clarity in writing, true and rousing depictions of suffering, that kind of thing.
Fair enough comment, and I love that you commented to justify the downvote. I respect that perspective that PR risk shouldn't be an important concern within EA and think its a reasonable argument, even though I disagree.
Thanks, Nick.
Bryan Walsh published a newsletter for Vox, Human progress has come at the expense of animals. It doesn’t have to., where there is a discussion of the EA Forum post Net global welfare may be negative and declining by Kyle Fish. In addition, "A version of this [Bryan's] newsletter originally appeared in the Future Perfect newsletter".
I do not think this is the relevant counterfactual. I assume ITNs (or malaria chemoprevention, or vaccines) save human lives more cost-effectively than the alternatives you mentioned. Otherwise, I would expect GiveWell to recommend them. So, to the extent people want to save lives as cost-effectively as possible, they will use the available resources to fight malaria to distribute ITNs. As a result, I think less donations to AMF simply result in less ITNs around.
I estimate 14.3 mosquito-days (= 51*365.25/0.013*10^-5) of excruciating pain neutralise the additional human welfare from saving a life under GW's moral weights multiplying:
Do the 3rd and 4th inputs seem "almost absurd"?
I was seeing much more than 1 mosquito per hour during dust outdoors in Moshi (Tanzania). People most affected by malaria may sleep indoors, but have houses with very limited ability to prevent mosquitoes from entering. The roofs can be made of turf too, which would attract mosquitoes.
I did not easily find empirical estimates for the number of mosquitoes killed by ITNs. I would be happy to update the number if you find them, although my takeaways would be the same even if ITNs only killed e.g. 10 % as many mosquitoes as I assumed.
As Bob Fischer said, "I don’t think you’ve said anything that should cause someone to question that headline result", "the ultimate question is whether our [RP's] decisions were wrong, not whether they can be construed as animal-friendly".
I don’t think the 3rd input is absurd, but I do think it is probably too animal friendly. Like I said in my critique, their moral range calculation basically ends up as probability of sentience x behaviour score, and because all animals exhibit some of the behaviours they measure I think especially for smaller animals this is likely to overestimate their welfare. RPs behaviour score only really allows for a narrow range of something like between like 20 and 100 so its almost impossible for any small animal to come out of RP’s moral weights caculation with a negligibly small moral weight. In the article I was trying to be very measured and not make huge calls, but if you’re asking me what I might have done differently to weight animal behaviours, then I’d say I would have allowed for a much bigger behaviour score range, perhaps through having more than a binary yes/no system on some of the behaviours – giving less complex pain response behaviors a fraction of more complex ones.
I think the 4th input seems absurd and I won’t rehash this much as many others have made arguments against your reasoning on this thread. You’re translating a figure which is on the upper bound of judging severe human pain (which like Bruce said, by definition can’t last long) directly onto what you think might be happening in mosquitos – a wildly different organism. On what grounds really would mosquitos dying of poisoning likely cause that severe pain at a best guess? I think its possible but very unlikely so I think it would be reasonable for the sake of conservatism to reduce this number by orders of magnitude.
4. On the number of mosquitos front for a start I don’t like comments like “my takeways would probably be the same even if….” Multipliers can add up, and we’re trying to move towards accuracy so I think it can be an unhelpful copout to question how much any element of an analysis matters – Rethink Priorities said things like this a number of times during their moral weights project which was a small red flag for me.
I agree there’s no empirical research on the mosquito number front, but from my perspective having travelled around Africa and living in a grass thatched hut and sleeping under a mosquito net for the last 10 years, 24 mosquitos killed a day on average per net seems extremely unlikely. That would be something like 240 million mosquitos killed by nets alone every day in Uganda – which seems to me perhaps plausible but unlikely. From a distance I think you could have been more conservative with your “best guess”
I’ve already discussed the RP thing above thanks!
I understand they are not directly comparable, but I guess the newsletters from Vox also reach a much wider audience who is less acceptable of controversial takes compared to readers of the EA Forum.
Do you mean you would account for other behavioural proxies for welfare capacity besides the 90 RP considered? Which ones? RP seemed to be super comprehensive.
I do not understand. RP did not have a binary system to determine the probability of sentience.
RP did not use a binary system to determine the welfare range conditional on sentience, and actually underestimated this by giving zero weight to proxies for which there was no information (see what I bolded below).
I do not understand what you are referring to. Which specific proxies do you think should be weighted more heavily?
For all the analyses relying on pain intensities I am aware of, from AIM and RP, the ratio between the intensity of a pain of a given category and that of another is the same across species. I have now asked Cynthia Schuck-Paim, who is the research director of WFP (the organisation defining the pain intensities).
I agree excruciating pain "can’t last long", but this is consistent with my estimate that ITNs cause 119 s of excruciating pain per mosquito they kill.
As I say in the post, my estimates for the time in pain come from aggregating 3 sets of estimates provided by WFP's GPT Pain-Track. My estimate of 119 s of excruciating pain may well not be accurate, but which evidence do you have for it being "possible but very unlikely" to be that long?
I agree. At the same time, I think it is worth having in mind how far one is from reversing the conclusions.
As I replied to Bruce:
Cynthia has just clarified the answer to both of the following questions can be "yes".
I think my assumption of constant ratios within and across species still makes sense as the most agnostic assumption.