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Some other factors not mentioned here but I sometimes think about:
-PETA used to do welfare campaigns and proudly own up their work on welfare campaigns when they talk about their history. But they stopped doing welfare campaigns around 10 years ago and even published public statements against some of the initiatives. I keep wondering whether that has anything to do with EA entering into space, refusing to fund PETA, and PETA withdrawing from welfare work to differentiate itself from welfare campaigning organisations in response. That would reduce cost-effectiveness of welfare campaigns significantly.
-One part I often see missing from human-animal comparisons is that animal welfare work prevents very extreme types suffering that would be classified as torture in human contexts. If I were to choose between extending a human life for 50 years versus preventing a person from suffering for one full year in a wire coffin, I would choose the latter. Similarly choosing between preventing 20.000 years of non-stop chicken torture vs. saving a human life is a lot different from saving the lives of 20.000 chickens versus saving the life of a human being. I think $5000 is currently able to fund alleviating 40000 years of chicken suffering by about half.
-Animals suffer from acts of deliberate violence. If acts of violence are also axiologically bad in themselves then there are more reasons to prevent violence than prevent deaths due to neglect. I don't endorse this position but I think it is aligned with folk ethics. People are willing to spend much more on preventing murders than preventing deaths due to natural causes.
-In animal welfare CEAs, it's often assumed that advocacy speeds up eventual progress by 10 years. I think that's a bit short. Here's one data point from France:
From 1997 to 2017, the number of hens in cages was reduced by 10 million hens in 20 years. In 2017, Open Philanthropy came in. After that, the number of hens in cages was reduced by 20 million hens in 7 years. If the rate of decline had remained constant, that reduction would have happened in 40 years instead.
-If we're in the business of speculating about sociological side effects of interventions, many animal activists like arguing that violence against animals is breeding ground for all kinds of violence. Calling people "cockroaches" or "rats" is an important part of legitimising violence. I don't like this type of arguments as they can be used to justify any type of intervention. But I think at the very least this should serve as an example to be wary of this kind of hardly falsifiable arguments.