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That's an interesting thought. But how exactly do you price that opposition in, since it presumably depends on the psychology of the people who run those companies? The degree to which companies are willing to fight various projects would make a huge difference, and they ultimately have more financial resources at their disposal than the EA movement. On a more optimistic note, maybe cases like the passage of Proposition 12 in California show that even these companies lack the power to stop certain well-targeted approaches. (fingers crossed that the new Farm Bill in the U.S. does not roll back this progress).
Is gene editing to reduce suffering available? There has been a good amount of research that shows knockouts of different aspects of pain and other negatively valenced states in laboratory animals. How close it is to being actually available would depend on what would be needed to get regulatory approval and what additional tests would be required in order to feel confident that the modifications are actually improving welfare (since we run into the epistemic questions about knowing what non-verbal animals are actually feeling).